European stocks were mixed at the opening bell on Wednesday, shrugging off the S&P 500 longest-ever bull-market run on Wall Street.
The pan-European STOXX 600 inched up less than 0.1 percent to 383.5.
Germany’s DAX also added less than 0.1 percent, while France’s CAC 40 Index was flat at 5,413. Britain's FTSE 100 fell 0.3 percent to 12,403 and was on course for its seventh session of losses of the past 10 trading days.
Belgium-based biopharma Argenx posted the best performance among the STOXX 600 firms, rising 6 percent after Abbvie announced an exclusive option to develop and put into civil circulation one of its experimental drugs.
Denmark’s Jyske Bank led the decline, losing 4.8 percent after posting its results for the second quarter.
Shares in Atlantia were up 1.2 percent. Italian state lender Cassa Depositi e Prestiti may be involved in a public takeover of Autostrade per l’Italia, following the Genoa bridge collapse that killed 43 people.