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Novartis Backs Full Year Forecast after $6B Profit Beat Helped by One-Offs

  • Novartis backs 2026 expectations for profit, sales
  • Shares rose 3.2% before paring some gains
  • Analysts expect some one-off benefits to reverse in H2

LONDON, July 21 - Novartis beat second-quarter profit forecasts and kept its 2026 outlook unchanged on Tuesday, ‌saying one-off benefits that helped the quarter would reverse as it increases research and launch spending in the second half.

The Swiss drugmaker's shares rose as much as 3% after it reported quarterly core operating profit of $5.94 billion, above analysts' predictions of about $5.31 billion cited by Visible Alpha.

Investors are closely watching several trial ​readouts expected later this year that could determine whether Novartis can sustain growth beyond its current patent cliff and ​support its premium valuation.

Late-stage data for three experimental drugs — pelacarsen in cardiovascular disease, remibrutinib in multiple sclerosis ⁠and del-desiran in myotonic dystrophy type 1 — represent a roughly $10 billion peak annual sales opportunity, according to analyst estimates.

"That first batch ​should come in the coming months," Chief Executive Vas Narasimhan told reporters, referring to the three trial results. He did not give ​a more precise timing.

Novartis, which has a market capitalization of about $310 billion after a 14% share rise so far this year, faces its most intense period of patent expiries, most notably for heart drug Entresto, which accounted for about 10% of total sales.

"Because they're getting hit by generic competition, patent cliffs ​are coming up, and there's only so much M&A you can do, the next stage is your pipeline," said James Eugene, ​analyst at Novartis shareholder Verso Investment Management.

Narasimhan also said Novartis did not need large deals, citing confidence in its internal pipeline. He said he planned to ‌stay ⁠at Novartis for its next phase of growth as the company moves past the Entresto patent cliff.

HIGHER SPENDING IN SECOND HALF

Novartis backed its forecast for low-single-digit sales growth and a low-single-digit decline in core operating profit this year, both excluding currency swings.

Chief Financial Officer Mukul Mehta said temporary sales and cost benefits boosted second-quarter sales by about 1% and core operating profit by about 5%, but these ​would reverse in the second ​half.

Novartis said core SG&A expenses ⁠fell 6% to $3.24 billion, helped by productivity gains, but analysts expect costs to rise from the third quarter as it absorbs its $12 billion acquisition of Avidity Biosciences and launches newer drugs.

RETURN TO SALES ​GROWTH

A U.S. inventory benefit for psoriasis drug Cosentyx and cost control helped Novartis post a 1% ​constant-currency rise in ⁠quarterly sales to $14.41 billion, ahead of expectations and its previous guidance for growth to return in the second half.

Kisqali sales rose 44% to $1.7 billion, Scemblix nearly doubled to $562 million and Cosentyx grew 12% to $1.82 billion, helped by a roughly $100 million stocking benefit.

Entresto sales fell 50% to $1.18 ⁠billion, worse ​than analysts forecast, due to generic competition in the U.S., its largest market. ​Entresto sales are expected to fall by $4 billion this year.

Vontobel analyst Stefan Schneider said the strong quarter did not trigger a guidance upgrade because timing of cost spending ​had "just moved around things" within the year.

Reporting by Bhanvi Satija and Marleen Kaesebier; Editing by Miranda Murray, Alexander Smith and Jon Boyle

Source: Reuters


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